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Friday, June 5, 2015

Immunology disorders

AIDS?
ØHuman immunodeficiency virus (HIV) infection may cause acquired immunodeficiency syndrome (AIDS).
ØAlthough characterized by gradual destruction of cell-mediated (T cell) immunity, AIDS also affects humoral immunity and even autoimmunity through the central role of the CD4+ (helper) T lymphocyte in all immune reactions.
ØThe resulting immunodeficiency makes the patient susceptible to opportunistic infections, cancers, and other  abnormalities that define AIDS.

ØHIV-1 retrovirus transmitted by contact with infected blood or body fluids
  HIGH-RISK POPULATIONS
ØHomosexual or bisexual men
ØI.V. drug users
ØNeonates of infected women
ØRecipients of contaminated blood or blood products
ØHeterosexual partners of persons in high-risk groups


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